Xanthine oxidase-IN-7

Names

[ CAS No. ]:
2411698-59-2

[ Name ]:
Xanthine oxidase-IN-7

Biological Activity

[Description]:

Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 µM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase

[Target]

IC50: 0.36 µM (XO)[1]


[References]

[1]. Gao J, et al. Design, synthesis and biological evaluation of 1-alkyl-5/6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors. Eur J Med Chem. 2020 Mar 15;190:112077.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H14N4O2

[ Molecular Weight ]:
294.31

Related Compounds