2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br

Names

[ CAS No. ]:
2411022-24-5

[ Name ]:
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br

Biological Activity

[Description]:

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br is a E3 ligase ligand-linker conjugate for PROTAC.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Wei D, et al. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14822-14847.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₁BrN₂O₃

[ Molecular Weight ]:
393.27

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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