Inupadenant hydrochloride

Names

[ CAS No. ]:
2411004-22-1

[ Name ]:
Inupadenant hydrochloride

Biological Activity

[Description]:

Inupadenant (EOS-850) hydrochloride is an orally active, highly selective A2A receptor antagonist. Inupadenant hydrochloride is not brain-penetrant. Inupadenant hydrochloride has potent anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[References]

[1]. Laurence Buisseret, et al. Phase 1 trial of the adenosine A2Areceptor antagonist inupadenant (EOS-850): Update on tolerability, and antitumor activity potentially associated with the expression of the A2A receptor within the tumor. Journal of Clinical Oncology. Volume 39, Issue 15_suppl.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H27ClF2N8O4S2

[ Molecular Weight ]:
641.11

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.