HIV-1 inhibitor-34

Names

[ CAS No. ]:
2395777-45-2

[ Name ]:
HIV-1 inhibitor-34

Biological Activity

[Description]:

HIV-1 inhibitor-34 (compound 5q) is a potent and selective HIV-1 inhibitor with an EC50 of 6.4 nM for HIV-1 and a CC50 of 16 μM in MT-4 cells. HIV-1 inhibitor-34 can be used for researching AIDS[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[Target]

HIV-1 (WT):6.4 nM (EC50)


[References]

[1]. Xiao T, et al. Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2020;186:111864.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H27N7O

[ Molecular Weight ]:
453.54

Related Compounds