SGLT1/2-IN-2

Names

[ CAS No. ]:
2387812-73-7

[ Name ]:
SGLT1/2-IN-2

Biological Activity

[Description]:

SGLT1/2-IN-2 demonstrates potent dual inhibitory activities (IC50 = 96 nM for SGLT1 and IC50 = 1.3 nM for SGLT2).

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT

[References]

[1]. Xu G, et al. 5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127387.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₆F₂O₇

[ Molecular Weight ]:
452.45

Related Compounds

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