hPL-IN-1

Names

[ CAS No. ]:
2387374-26-5

[ Name ]:
hPL-IN-1

Biological Activity

[Description]:

hPL-IN-1 (compound 2t) is a reversible inhibitor of pancreatic lipase (PL) (IC50=1.86 μM) for anti-obesity research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

IC50: 1.86 μM (Pancreatic lipase, PL)[1]

[References]

[1]. Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413.. .

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₁Cl₂F₂NO₃

[ Molecular Weight ]:
410.20

[ Storage condition ]:
-20℃

Related Compounds

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