BCL6-IN-9

Names

[ CAS No. ]:
2378852-76-5

[ Name ]:
BCL6-IN-9

Biological Activity

[Description]:

BCL6-IN-9 (compound 1) is a potent B-cell lymphoma 6 protein (BCL6) inhibitor, with an IC50 of 3.9 nM. BCL6-IN-9 can be used for the research of cancer[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[Target]

IC50: 3.9 nM (B-cell lymphoma 6 protein)[1]


[References]

[1]. Davis OA, et, al. Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors. J Med Chem. 2022 Jun 3.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H18ClF2N5O2

[ Molecular Weight ]:
457.86

Related Compounds