Antitumor agent-122

Names

[ CAS No. ]:
2378641-43-9

[ Name ]:
Antitumor agent-122

Biological Activity

[Description]:

Antitumor agent-122 (Compound 5j) is an antitumor agent with good efficacy, limited toxicity and low resistance. Antitumor agent-122 has antiproliferative activity for MGC-803 cell, HepG2 cell, SKOV3 cell and T24 cell with IC50 values of 5.23 μM, 3.60 μM, 1.43 μM, 3.03 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50: 5.23 μM (MGC-803 cell), 3.60 μM (HepG2 cell), 1.43 μM (SKOV3 cell), 3.03 μM (T24 cell)[1]


[References]

[1]. Liang SM, et al. Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance. Eur J Med Chem. 2023 Nov 10;263:115937.  

Chemical & Physical Properties

[ Molecular Formula ]:
C28H30N4O2S2

[ Molecular Weight ]:
518.69

Related Compounds

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