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VHL Ligand-Linker Conjugates 15

Names

[ CAS No. ]:
2375564-62-6

[ Name ]:
VHL Ligand-Linker Conjugates 15

Biological Activity

[Description]:

VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

VHL


[References]

[1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

Chemical & Physical Properties

[ Molecular Formula ]:
C37H45FN4O8S

[ Molecular Weight ]:
724.84

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds