JHU 37160

Names

[ Name ]:
JHU 37160

[Synonym ]:
MFCD20727945

Biological Activity

[Description]:

JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₀ClFN₄

[ Molecular Weight ]:
358.8403

Related Compounds

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