Damascenone

Names

[ Name ]:
Damascenone

[Synonym ]:
3,5,8-Megastigmatrien-7-one
MFCD00101024
FEMA 3420
Fema no. 3420
2-Buten-1-one, 1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-
Einecs 245-833-2
1-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)-2-buten-1-one
DAMASCENON
Damasione
Trimethyl cyclohexadienyl butenone
DAMASCENONE TOTAL

Biological Activity

[Description]:

Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity[1]. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[In Vitro]

β-Damascenone also inhibits the upregulation of inflammatory proteins as demonstrated by immune assays for cell surface E-selectin and secreted TNF-α[1]. β-Damascenone inhibits NF-κB signaling pathway in vitro in human cellular systems that has been activated with different inflammatory stimuli[1].

[References]

[1]. San-Po Pan, et al. C13 Megastigmane Derivatives From Epipremnum pinnatum: β-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-κB Signaling

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
275.6±10.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₈O

[ Molecular Weight ]:
190.281

[ Flash Point ]:
111.0±14.0 °C

[ Exact Mass ]:
190.135757

[ PSA ]:
17.07000

[ LogP ]:
4.04

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.491

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H317-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P370 + P378-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S7-S16

[ RIDADR ]:
UN 1170

[ HS Code ]:
2914299000

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Instrumental and sensory approaches for the characterization of compounds responsible for wine aroma.

Chem. Biodivers. 5(6) , 1170-83, (2008)

More than 800 aromatic compounds have been identified in wine, some of them at the ng/l level. Wine, therefore, constitutes a very complex matrix, from which it is difficult to isolate a specific arom...

Identification and quantification of aroma-active components that contribute to the distinct malty flavor of buckwheat honey.

J. Agric. Food Chem. 50(7) , 2016-21, (2002)

Characteristic aroma components of buckwheat honey were studied by combined sensory and instrumental techniques. Relative aroma intensity of individual volatile components was evaluated by aroma extra...

Simultaneous determination of E-2-nonenal and beta-damascenone in beer by reversed-phase liquid chromatography with UV detection.

J. Chromatogr. A. 1032(1-2) , 17-22, (2004)

A method for the simultaneous determination of E-2-nonenal and beta-damascenone in beer by reversed-phase liquid chromatography using UV detection is presented. The method consists of beer steam disti...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.