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6,9-Metheno-9H-1,3-dioxino[4,5,6-uv][4]benzazacyclotricosine-20-carboxylicacid,7-(acetyloxy)-5,10,11,16,17,18,19,20,21,22,23,24-dodecahydro-17,19,21,23,24,27-hexahydroxy-4,8,12,16,18,22,24,26-octameth

Names

[ CAS No. ]:
23344-17-4

[ Name ]:
6,9-Metheno-9H-1,3-dioxino[4,5,6-uv][4]benzazacyclotricosine-20-carboxylicacid,7-(acetyloxy)-5,10,11,16,17,18,19,20,21,22,23,24-dodecahydro-17,19,21,23,24,27-hexahydroxy-4,8,12,16,18,22,24,26-octameth

[Synonym ]:
U-8741
STREPTOVARICIN C
streptovaricinoic acid methyl ester
Streptovaricinsaeure-methylester
Streptovaricin complex,fraction c

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
843.6ºC at 760mmHg

[ Molecular Formula ]:
C40H51NO14

[ Molecular Weight ]:
769.83100

[ Flash Point ]:
464ºC

[ Exact Mass ]:
769.33100

[ PSA ]:
238.61000

[ LogP ]:
3.24260

[ Vapour Pressure ]:
4.42E-33mmHg at 25°C

[ Index of Refraction ]:
1.621

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WK5880000
CHEMICAL NAME :
Streptovaricin C
CAS REGISTRY NUMBER :
23344-17-4
LAST UPDATED :
199309
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C40-H51-N-O14
MOLECULAR WEIGHT :
769.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
233 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Phage inhibition capacity
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
100 pg/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,2819,1983

Precursor & DownStream


Related Compounds

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