USP7-866

Names

[ Name ]:
USP7-866

Biological Activity

[Description]:

USP7-866 is a novel potent selective inhibitor of USP7 with IC50 of 0.18 nM;USP7-866 inhibited the growth of p53-mutant small cell lung cancer cell line H526 at a CC50 of 42 nM.

[References]

1. Yamini M Ohol, et al. Mol Cancer Ther. 2020 Oct;19(10):1970-1980. 2. Paul R Leger, et al. J Med Chem. 2020 May 28;63(10):5398-5420.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₀ClN₃O₃S

[ Molecular Weight ]:
524.076

Related Compounds

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