ERK5-IN-5

Names

[ Name ]:
ERK5-IN-5

Biological Activity

[Description]:

ERK5-IN-5 (compound 4a) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-5 exhibits good anti-proliferative activity with the IC50 value of 6.23 µg/mL for A549 cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> ERK

Signaling Pathways >> Stem Cell/Wnt >> ERK

[Target]

ERK5

[References]

[1]. Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆ClN₃O

[ Molecular Weight ]:
337.80

[ Storage condition ]:
-20℃

ERK5-IN-5

Names

Biological Activity

Chemical & Physical Properties

Related Compounds