FAK ligand-Linker Conjugate 1

Names

[ Name ]:
FAK ligand-Linker Conjugate 1

Biological Activity

[Description]:

FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₈F₃N₅O₆S

[ Molecular Weight ]:
583.58

Related Compounds

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