4-Chloro-3-nitro-5-sulphamoylbenzoic acid

Names

[ Name ]:
4-Chloro-3-nitro-5-sulphamoylbenzoic acid

[Synonym ]:
Benzoic acid, 3-(aminosulfonyl)-4-chloro-5-nitro-
4-Chloro-3-nitro-5-sulfamoylbenzoic acid
EINECS 245-310-9
MFCD00058688
4-Chloro-3-nitro-5-sulfamoylbenzoicAcid
4-Chloro-3-nitro-5-sulfamoyl benzoic acid

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
563.5±60.0 °C at 760 mmHg

[ Melting Point ]:
227-231ºC

[ Molecular Formula ]:
C₇H₅ClN₂O₆S

[ Molecular Weight ]:
280.642

[ Flash Point ]:
294.6±32.9 °C

[ Exact Mass ]:
279.955688

[ PSA ]:
151.66000

[ LogP ]:
1.13

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.649

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Ultrasound mediated catalyst free synthesis of 6H-1-benzopyrano[4,3-b]quinolin-6-ones leading to novel quinoline derivatives: their evaluation as potential anti-cancer agents.

Bioorg. Med. Chem. 20 , 759-68, (2012)

A facile and catalyst free synthesis of 6H-1-benzopyrano[4,3-b]quinolin-6-ones has been accomplished via the reaction of 4-chloro-2-oxo-2H-chromene-3-carbaldehyde with various aromatic amines in the p...