1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]

Names

[ Name ]:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]

[Synonym ]:
9,11,15-Trioxa-6-aza-10-phosphatritriacont-24-enoicacid,10-hydroxy-5,16-dioxo-13-[[(9Z)-1-oxo-9-octadecenyl]oxy]-,10-oxide,(13R,24Z)-(9CI)
9,11,15-Trioxa-6-aza-10-phosphatritriacont-24-enoicacid,10-hydroxy-5,16-dioxo-13-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-,10-oxide,(13R,24Z)

Biological Activity

[Description]:

DOPE-GA can be used for formulation of liposome, and used in the research of drug delivery[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Cuvillier O, et al. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling. Blood. 1999 Nov 15;94(10):3583-92.

[2]. Perkins WR, et al. Novel therapeutic nano-particles (lipocores): trapping poorly water soluble compounds. Int J Pharm. 2000 Apr 25;200(1):27-39.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₈₄NO₁₁P

[ Molecular Weight ]:
858.13300

[ Exact Mass ]:
857.57800

[ PSA ]:
188.06000

[ LogP ]:
12.86140

Related Compounds

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