BC-05

Names

[ Name ]:
BC-05

Biological Activity

[Description]:

BC-05 is an orally active and potent inhibitor of CD13 and proteasome. BC-05 has an IC50 value of 0.13 μM for human CD13 and an IC50 value of 1.39 μM for the 20S proteasome. BC-05 can be used in multiple myeloma research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

[References]

[1]. Zhang J, et al. Discovery of a Novel Ubenimex Derivative as a First-in-Class Dual CD13/Proteasome Inhibitor for the Treatment of Cancer. Molecules. 2023 Aug 30;28(17):6343.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₉BN₂O₉

[ Molecular Weight ]:
464.27