DBCO-(PEG2-VC-PAB-MMAE)2

Names

[ Name ]:
DBCO-(PEG2-VC-PAB-MMAE)2

Biological Activity

[Description]:

DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Auristatin

[References]

[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₉H₂₂₄N₂₂O₃₂

[ Molecular Weight ]:
2835.50

Related Compounds

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