Resiquimod-d5

Names

[ Name ]:
Resiquimod-d5

Biological Activity

[Description]:

Resiquimod-d5 (R848-d5) is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Signaling Pathways >> Anti-infection >> HCV

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[References]

[1]. Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32.

[2]. Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₇D₅N₄O₂

[ Molecular Weight ]:
319.41

Related Compounds

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