RTICBM-229

Names

[ Name ]:
RTICBM-229

[Description]:

RTICBM-229 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 169 nM in Ca2+ assay, 40 nM in GTPγS assay.

[References]

1. Thuy Nguyen, et al. J Med Chem. 2019 Nov 14;62(21):9806-9823.

[ Molecular Formula ]:
C₁₇H₁₄ClN₃O

[ Molecular Weight ]:
311.769