JWD-065

Names

[ Name ]:
JWD-065

Biological Activity

[Description]:

JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.

[References]

1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55. 2. Miduturu CV et al. Chem Biol. 2011;18:868–879.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₆N₆O₂S

[ Molecular Weight ]:
462.572

Related Compounds

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