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Nor NOHA monoacetate

Names

[ CAS No. ]:
2250019-93-1

[ Name ]:
Nor NOHA monoacetate

Biological Activity

[Description]:

nor-NOHA (Nω-Hydroxy-nor-L-arginine) monoacetate is a potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat liver arginase with a Ki of 0.5 µM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> Immunology/Inflammation >> Arginase

[References]

[1]. Tenu JP, et al. Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages. Nitric Oxide. 1999;3(6):427-438.

[2]. Custot J, et al. A new α-amino acid N w -hydroxy-nor-L-arginine: A highly-affinity inhibitor of arginase well adapted to bind to its manganese cluster.Journal of the American Chemical Society 119, 4086-4087(1997).

Chemical & Physical Properties

[ Molecular Formula ]:
C7H16N4O5

[ Molecular Weight ]:
236.23

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds