benz(a)acridine

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
446.2±14.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₁N

[ Molecular Weight ]:
229.276

[ Flash Point ]:
201.4±12.7 °C

[ Exact Mass ]:
229.089142

[ PSA ]:
12.89000

[ LogP ]:
4.63

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.783

[ Storage condition ]:
2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :

CU2700000

CHEMICAL NAME :

Benz(a)acridine

CAS REGISTRY NUMBER :

225-11-6

BEILSTEIN REFERENCE NO. :

0009262

LAST UPDATED :

199612

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933990090

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Substituted benz[a]acridines and benz[c]acridines as mammalian topoisomerase poisons.

Bioorg. Med. Chem. 8(5) , 1171-82, (2000)

Coralyne and several other synthetic benzo[a,g]quinolizium derivatives related to protoberberine alkaloids have exhibited activity as topoisomerase poisons. These compounds are characterized by the pr...

Benz[a]acridine.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 123-7, (1983)

Mutagenicity of diol-epoxides and tetrahydroepoxides of benz(a)acridine and benz(c)acridine in bacteria and in mammalian cells.

Cancer Res. 43(4) , 1656-62, (1983)

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