NPB

Names

[ CAS No. ]:
2247491-97-8

[ Name ]:
NPB

Biological Activity

[Description]:

NPB is a specific and potent inhibitor of BAD phosphorylation at Ser99, with an IC50 of 0.41 μM[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family

Research Areas >> Cancer

[Target]

IC50: 0.41 μM (BAD at Ser99)[1]

[References]

[1]. Pandey V, et al. Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10505-E10514.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₁Cl₂N₃O₂

[ Molecular Weight ]:
524.48

Related Compounds

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