BAY-293 racemate

Names

[ Name ]:
BAY-293 racemate

Biological Activity

[Description]:

BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM).

[References]

References 1. Hillig RC, et al. Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201812963. doi: 10.1073/pnas.1812963116. View Related Products by Target Ras

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₈N₄O₂S

[ Molecular Weight ]:
448.585

Related Compounds

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