LRH-1 modulator-1

Names

[ Name ]:
LRH-1 modulator-1

Biological Activity

[Description]:

LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Mays SG, et al. Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design. J Med Chem. 2019 Dec 26;62(24):11022-11034.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₆N₂O₂S

[ Molecular Weight ]:
464.66

Related Compounds

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