Integracin B

Names

[ Name ]:
Integracin B

[Synonym ]:
integracin b

Biological Activity

[Description]:

Integracin B is a potent dimeric alkyl aromatic inhibitor of HIV-1 integrase discovered from the screening of fungal extracts using an in vitro assay. Integracin B inhibits both coupled and strand transfer activity of HIV-1 integrase[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Integrase

[References]

[1]. Sheo B.Singh, et al. Discovery, structure and HIV-1 integrase inhibitory activities of integracins, novel dimeric alkyl aromatics from Cytonaema sp. Tetrahedron Letters. 2002 February 25, 43 (9): 1617-1620.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₅₄O₇

[ Molecular Weight ]:
586.79900

[ Exact Mass ]:
586.38700

[ PSA ]:
127.45000

[ LogP ]:
8.46190

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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