AUTAC2
Names
[ CAS No. ]:
2241669-08-7
[ Name ]:
AUTAC2
Biological Activity
[Description]:
AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12[1].
[Related Catalog]:
[In Vitro]
AUTAC1 (1-100 μM, 24 h) silences endogenous FKBP12 in hela cells[1]. Western Blot Analysis[1] Cell Line: HeLa cells. Concentration: 0-100 μM. Incubation Time: 24 h. Result: Silenced endogenous FKBP12.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C61H81FN10O14S
[ Molecular Weight ]:
1229.42
Related Compounds
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