E3 ligase Ligand 14

Names

[ CAS No. ]:
2241489-43-8

[ Name ]:
E3 ligase Ligand 14

Biological Activity

[Description]:

E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

Chemical & Physical Properties

[ Molecular Formula ]:
C38H52N4O7

[ Molecular Weight ]:
676.84

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds