IACS-8968 R-enantiomer

Names

[ CAS No. ]:
2239305-67-8

[ Name ]:
IACS-8968 R-enantiomer

Biological Activity

[Description]:

IACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
Research Areas >> Cancer

[Target]

IDO, TDO[1].


[References]

[1]. ARYL SULFONOHYDRAZIDES. WO 2017189386 A1


[Related Small Molecules]

Epacadostat(INCB024360) | Indoximod | Linrodostat (BMS-986205) | NLG919 | Coptisine chloride | Navoximod | INCB024360 analogue | PF-06840003 | GNF-PF-3777 | IDO-IN-4 | IDO-IN-1 | IDO-IN-12 | IDO-IN-2 | IDO-IN-3

Chemical & Physical Properties

[ Molecular Formula ]:
C17H18F3N5O2

[ Molecular Weight ]:
381.35

Related Compounds