Favezelimab

Names

[ CAS No. ]:
2231068-83-8

[ Name ]:
Favezelimab

Biological Activity

[Description]:

Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902)[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Carmen Belli, et al. Targeting Cellular Components of the Tumor Microenvironment in Solid Malignancies. Cancers (Basel). 2022 Sep 1;14(17):4278.  

[2]. Gareth P. Gregory, et al. Abstract CT106: Anti-LAG-3 antibody MK-4280 in combination with pembrolizumab for the treatment of hematologic malignancies: A Phase I/II study.  Cancer Res (2019) 79 (13_Supplement): CT106.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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