BTK inhibitor 1;Compound 27

Names

[ Name ]:
BTK inhibitor 1;Compound 27

Biological Activity

[Description]:

BTK inhibitor 8 (Compound 27) is a Btk inhibitor with an IC50 of 0.11 nM. BTK inhibitor 8 inhibits B cell activation in hWB with an IC50 of 2 nM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Musumeci F, et al. Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors. Expert Opin Ther Pat. 2017 Dec;27(12):1305-1318.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₃FN₈O₂

[ Molecular Weight ]:
474.49

[ Storage condition ]:
Store at -20°C

[ Water Solubility ]:
DMSO ：95 mg/mL (200.21 mM)

Safety Information

[ Hazard Codes ]:
N

Related Compounds

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