ZL0590

Names

[ Name ]:
ZL0590

Biological Activity

[Description]:

ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

IC50: 90 nM (human BRD4 BD1)[1]

[References]

[1]. Liu Z, et al. Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site. J Med Chem. 2022;65(3):2388-2408.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₇F₃N₄O₄S

[ Molecular Weight ]:
512.55

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.