(R)-Elexacaftor

Names

[ Name ]:
(R)-Elexacaftor

Biological Activity

[Description]:

(R)-Elexacaftor is an enantiomer of Elexacaftor (HY-111772). (R)-Elexacaftor is the Compound 37 from patent WO2018107100A1. (R)-Elexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR), the EC50 for CFTR dF508 is 0.29 uM[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR

Research Areas >> Inflammation/Immunology

[References]

[1]. Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator. WO2018107100A1

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₄F₃N₇O₄S

[ Molecular Weight ]:
597.65

(R)-Elexacaftor

Names

Biological Activity

Chemical & Physical Properties

Related Compounds