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Mirzotamab

Names

[ CAS No. ]:
2229859-11-2

[ Name ]:
Mirzotamab

Biological Activity

[Description]:

Mirzotamab is an IgG1κ antibody targeting to CD276/B7-H3. Mirzotamab can conjugates with Clezutoclaxum (HY-137774), an BCL2L1 inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane therapy in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC)[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

CD276/B7-H3[1]


[References]

[1]. Tolcher A W, et al. A first-in-human study of mirzotamab clezutoclax as monotherapy and in combination with taxane therapy in relapsed/refractory solid tumors: Dose escalation results. 2021.

Chemical & Physical Properties

No Any Chemical & Physical Properties


Related Compounds

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