BTM-3566

Names

[ Name ]:
BTM-3566

Biological Activity

[Description]:

BTM-3566 is an OMA1 activator. BTM-3566 activates the mitochondrial stress response. BTM-3566 induces apoptosis in diffuse large B-cell lymphomas (DLBCL) cell lines[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Schwarzer A, et al. Targeting aggressive B-cell lymphomas through pharmacological activation of the mitochondrial protease OMA1. Mol Cancer Ther. 2023 Aug 30.

[2]. Adrian Schwarzer, et al. Btm-3566, a Novel Activator of the Mitochondrial Stress Response Promotes Robust Therapeutic Responses in Vitro and In Vivo in Diffuse Large B-Cell Lymphoma. Blood. Volume 138, Supplement 1, 23 November 2021, Page 684.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₃F₄N₃O₂S₂

[ Molecular Weight ]:
525.58

Related Compounds

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