SHP504

Names

[ CAS No. ]:
2222280-83-1

[ Name ]:
SHP504

[Synonym ]:
3-(4-(2-chlorobenzyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl)-4-hydroxybenzoic acid

Biological Activity

[Description]:

SHP504 is a SHP2 phosphatase inhibitor, with an IC50 of 21 μM for SHP21–525[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

[References]

[1]. Michelle Fodor, et al. Dual Allosteric Inhibition of SHP2 Phosphatase. ACS Chem Biol. 2018 Mar 16;13(3):647-656.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₅ClN₄O₄

[ Molecular Weight ]:
446.84

[ Storage condition ]:
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.