Thymohydroquinone

Names

[ Name ]:
Thymohydroquinone

[Synonym ]:
Hydrothymoquinone
1,4-dihydroxy-2-isopropyl-5-methylbenzene
2-Isopropyl-5-methylbenzene-1,4-diol
p-Cymene-2,5-diol (8CI)
4-Hydroxy-5-isopropyl-2-methylphenol
Hydroquinone,5-isopropyl-2-methyl
2-Isopropyl-5-methylhydroquinone
1,4-Benzenediol, 2-methyl-5-(1-methylethyl)-
2-isopropyl-5-methyl-p-hydroquinone
1,4-Benzenediol, 2-methyl-5- (1-methylethyl)-
Thymoquinol
Thymohydroquinone
2-methyl-5-(propan-2-yl)benzene-1,4-diol
2-Methyl-5-isopropylhydroquinone
2-Isopropyl-5-methyl-1,4-benzenediol
2-hydroxythymol
p-Cymene-2,5-diol

Biological Activity

[Description]:

Thymohydroquinone is a monoterpene molecule. Thymohydroquinone has antioxidant and anti-inflammatory properties. Thymohydroquinone can be used for pharmacokinetic studies and regulatory toxicity studies [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Goyal SN, et al. Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin. Front Pharmacol. 2017 Sep 21;8:656.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
306.4±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₄O₂

[ Molecular Weight ]:
166.22

[ Flash Point ]:
147.9±21.1 °C

[ Exact Mass ]:
166.099380

[ PSA ]:
40.46000

[ LogP ]:
2.44

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.555

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MX6680000

CHEMICAL NAME :: Hydroquinone, 5-isopropyl-2-methyl-

CAS REGISTRY NUMBER :: 2217-60-9

BEILSTEIN REFERENCE NO. :: 2084452

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H14-O2

MOLECULAR WEIGHT :: 166.24

WISWESSER LINE NOTATION :: QR DQ B1 EY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,1227,1965

Safety Information

[ HS Code ]:
2907299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%