Zeteletinib

Names

[ Name ]:
Zeteletinib

Biological Activity

[Description]:

Zeteletinib (BOS-172738) shows selective inhibitory activity against RET, PDGFR, KIT, NTRK and FLT3 kinases. Zeteletinib has antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Kit

[Target]

PDGFR

[References]

[1]. Inagaki, Hiroaki, et al.Preparation of pyridine compound as RET kinase inhibitors.WO2018060714A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₃F₃N₄O₄

[ Molecular Weight ]:
500.47

Related Compounds

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