1-Piperidinamine
Names
[ CAS No. ]:
2213-43-6
[ Name ]:
1-Piperidinamine
[Synonym ]:
1-aminopiperidine
N-Piperidylamine
piperidin-1-ylamine
1-Piperidinamine
1-Piperidinamine (9CI)
1-amino-piperidine
PIPERIDINE,1-AMINO
EINECS 218-666-8
N-Aminopiperidine
Pentamethylenehydrazine Piperidin-1-ylamine
N,N-pentamethylenehydrazine
1-piperidinylamine
piperidin-1-amine
MFCD00006489
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
146.9±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C5H12N2
[ Molecular Weight ]:
100.162
[ Flash Point ]:
36.1±0.0 °C
[ Exact Mass ]:
100.100044
[ PSA ]:
29.26000
[ LogP ]:
-0.28
[ Vapour Pressure ]:
4.5±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.486
[ Storage condition ]:
Flammables area
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM4165000
- CHEMICAL NAME :
- Piperidine, 1-amino-
- CAS REGISTRY NUMBER :
- 2213-43-6
- BEILSTEIN REFERENCE NO. :
- 0383565
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C5-H12-N2
- MOLECULAR WEIGHT :
- 100.19
- WISWESSER LINE NOTATION :
- T6NTJ AZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 3 umol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 91,199,1981
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C: Corrosive;
[ Risk Phrases ]:
R10;R20/21/22;R34
[ Safety Phrases ]:
S16-S26-S36/37/39-S45
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
TM4165000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Biol. Chem. 290 , 20313-24, (2015)
Historically, type II topoisomerases have yielded clinically useful drugs for the treatment of bacterial infections and cancer, but the corresponding enzymes from malaria parasites remain understudied...
Inhibition of metabolism--mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma cells (line P815).Adv. Exp. Med. Biol. 136 Pt B , 1067-75, (1981)
Aerial oxidation of hydrazines to nitrosamines.
Environ. Mol. Mutagen. 17(1) , 59-62, (1991)
When 1,1-dimethylhydrazine and N-aminopiperidine were deliberately exposed to air substantial amounts of the corresponding carcinogenic nitrosamines were formed. Unoxidized samples of 1,1-dimethylhydr...