Mosedipimod

Names

[ Name ]:
Mosedipimod

[Synonym ]:
1-(acetyloxy)-3-(hexadecanoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
1-Acetoxy-3-(palmitoyloxy)-2-propanyl (9Z,12Z)-9,12-octadecadienoate
9,12-Octadecadienoic acid, 2-(acetyloxy)-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester, (9Z,12Z)-
Mosedipimod

Biological Activity

[Description]:

Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro; attenuates the asthmatic response in an aluminum hydroxide/ovalbumin-induced model of asthma, inhibits hematogenous metastasis of KIGB-5 biliary cancer cell in hamster model. Other Indication Phase 2 Clinical

[References]

References 1. Yoon SY, et al. Immune Netw. 2015 Apr;15(2):100-9. 2. Shin IS, et al. Int Immunopharmacol. 2016 Jan;30:62-68. 3. Shin IS, et al. Int Immunopharmacol. 2014 Jan;18(1):116-23. 4. Kim MH, et al. J Korean Med Sci. 2009 Jun;24(3):474-80. View Related Products by Target Other Targets Other Indication

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
650.6±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₉H₇₀O₆

[ Molecular Weight ]:
634.969

[ Flash Point ]:
257.4±26.0 °C

[ Exact Mass ]:
634.517212

[ LogP ]:
14.67

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.473

Related Compounds

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