Eculizumab

Names

[ CAS No. ]:
219685-50-4

[ Name ]:
Eculizumab

Biological Activity

[Description]:

Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Immunology/Inflammation >> Complement System

[References]

[1]. Eline A Dubois,et al. Eculizumab. Br J Clin Pharmacol. 2009 Sep;68(3):318-9.

Chemical & Physical Properties

[ Storage condition ]:
-20°C

Related Compounds

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