mDPR-Val-Cit-PAB-MMAE TFA

Names

[ CAS No. ]:
2185872-76-6

[ Name ]:
mDPR-Val-Cit-PAB-MMAE TFA

Biological Activity

[Description]:

mDPR-Val-Cit-PAB-MMAE TFA is a drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and an ADC linker (peptide Val-Cit- PAB) composition[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Moquist, et al. Preparation of drug conjugates of IgG1 antibodies with self-stabilizing linkers having improved physiochemical properties for treating cancers and autoimmune diseases. World Intellectual Property Organization, WO2018031690 A1. 2018-02-15.

Chemical & Physical Properties

[ Molecular Formula ]:
C67H101F3N12O17

[ Molecular Weight ]:
1403.58

Related Compounds

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