Vin-F03

Names

[ Name ]:
Vin-F03

Biological Activity

[Description]:

Vin-F03 is a potent pancreatic β-cells protective agent with an EC50 of 0.27 µM. Vin-F03 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-F03 can be used for type 2 diabetes mellitus research[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cardiovascular Disease

[Target]

EC50: 0.27 µM (pancreatic β-cells)[1]

[References]

[1]. Wang J, et al. Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus. Eur J Med Chem. 2020 Feb 15;188:111976.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₉N₃

[ Molecular Weight ]:
335.49

Related Compounds

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