2-Propenoic acid,ethenyl ester

Names

[ Name ]:
2-Propenoic acid,ethenyl ester

[Synonym ]:
Ethenyl acrylate
ethenyl 2-propenoate
2-propenoic acid,ethenyl ester
acrylic acid,vinyl ester
ethenyl prop-2-enoate
Propenoic acid ethenyl ester
EINECS 218-538-1
3-Oxahexa-1,5-diene-4-one

Chemical & Physical Properties

[ Density]:
0.936g/cm3

[ Boiling Point ]:
91.5ºC at 760mmHg

[ Molecular Formula ]:
C₅H₆O₂

[ Molecular Weight ]:
98.09990

[ Flash Point ]:
13.5ºC

[ Exact Mass ]:
98.03680

[ PSA ]:
26.30000

[ LogP ]:
0.85910

[ Vapour Pressure ]:
53.7mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.432(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD3341000

CHEMICAL NAME :: 2-Propenoic acid, ethenyl ester

CAS REGISTRY NUMBER :: 2177-18-6

LAST UPDATED :: 199806

DATA ITEMS CITED :: 5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0529778-1

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0529778-1 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 90 uL/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0529778-1

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1450 ppm/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - corneal damage Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0529778-1

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H300-H315-H318-H331

[ Precautionary Statements ]:
P210-P261-P264-P280-P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-25-34

[ Safety Phrases ]:
S9;S16;S26;S45;S36/S37/S39

[ RIDADR ]:
UN 3286 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
UD3341000

[ HS Code ]:
2915320000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916129000

[ Summary ]:
2916129000 other esters of acrylic acid VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Covalent Incorporation of Trehalose within Hydrogels for Enhanced Long-Term Functional Stability and Controlled Release of Biomacromolecules.

Adv. Healthc. Mater. 4 , 1802-12, (2015)

Hydrogels with covalently incorporated trehalose are synthesized using thiol-ene Michael addition. Trehalose hydrogels afford prolonged stabilization and -controlled release of model enzymes in vitro ...