Cjoc42

Names

[ Name ]:
Cjoc42

Biological Activity

[Description]:

Cjoc42 is a compound capable of binding to gankyrin. Cjoc42 inhibits gankyrin activity in a dose-dependent manner. Cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin. Cjoc42 restores p53-dependent transcription and sensitivity to DNA damage[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> MDM-2/p53

[References]

[1]. Chattopadhyay A, et al. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016;6:23732.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁N₃O₅S

[ Molecular Weight ]:
415.46

Related Compounds

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