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Eupalinolide O

Names

[ CAS No. ]:
2170228-67-6

[ Name ]:
Eupalinolide O

Biological Activity

[Description]:

Eupalinolide O is a sesquiterpene lactone with anticancer activities. Eupalinolide O induces cell apoptosis in human MDA-MB-468 breast cancer cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[In Vitro]

Eupalinolide O could induce cell cycle arrest and apoptosis in human MDA-MB-468 breast cancer cells. Eupalinolide O also shows anti-TNBC (triple-negative breast cancer) activity against human MDA-MB-468 breast cancer cells[1].

[References]

[1]. Bo Yang, et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H26O8

[ Molecular Weight ]:
418.44

Related Compounds