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PD-1/PD-L1-IN 5

Names

[ CAS No. ]:
2170209-51-3

[ Name ]:
PD-1/PD-L1-IN 5

Biological Activity

[Description]:

PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Research Areas >> Inflammation/Immunology

[Target]

IC50: ≤100 nM (PD-1/PD-L1)[1]


[In Vitro]

The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].

[References]

[1]. Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H18N4O3S

[ Molecular Weight ]:
418.47

Related Compounds