PD-1/PD-L1-IN-20

Names

[ CAS No. ]:
2159138-01-7

[ Name ]:
PD-1/PD-L1-IN-20

Biological Activity

[Description]:

PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[References]

[1]. Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H26BrClN2O3

[ Molecular Weight ]:
577.90

Related Compounds

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